While on vacation in Romania, Josh, the main character, and his wife Kate are on a train with several other tourists.

On his way, he encounters many travelers, such as a grandfather - Gregor, a student - Lin, two ballerinas called Sacha and Tasha; four teenagers - Monica, Max, Aaron and Katja - heading to a rave; an English psychiatrist called Jane; two Romanian generals; a Romanian ticket collector; a German businessman; and Yeli, a fortune-teller who gives Josh a grim prediction.

Bursting into the car, he find his wife being carried out by a large man with an odd-looking mechanism on his face.

Josh and Yeli follow, catching a glimpse of a strange man who is laughing maniacally.

Josh awakens to find the train in a river, and tries to save the ticket collector but fails.

After escaping the swamp and walking through the forest, they come upon a cemetery where they meet up with another group of survivors, Aaron, Sacha and Tasha.

As Josh makes his way through the cemetery, he hears a scream and watches as Monica is decapitated by Ernst (the man who abducted his wife) and then thrown at a wall.

Josh awakens to find that he has been tied to a chair by Viktor, the mad scientist responsible for the zombies.

He is about to kill Josh when he gets a phone call and exits urgently, leaving a zombie nurse to finish the job.

The two make their way through a hall when the survivor inspects a fresh bloodstain, only to end up bisected by a trap.

Josh then wanders to the top of the tower to find the raver couple, now resembling marionettes.

He kills them, and then is transported to a cave, where he picks up a mystical weapon, Azoth, that attaches to his left hand.

However, before he can reach Kate, Marchosias, or Fido in his human form, knocks Josh unconscious.

Josh wakes up to find that he is strapped to a vertical table, with the bodies of Viktor and Ernst present too.

Soon, Josh hears Aaron and Katja, who have escaped from their cell, an event that happens at the start of the game.

They open all the cell doors, and Josh tries to follow them, but they scream and run away because they think that he is Ernst.

Josh escapes, and also has the advantage of Ernst's two chain hands that can kill an enemy from a distance.

He encounters the man who told him of his wife's letter, and he thinks briefly about how he hates travelling through the cursed forest.

Josh then sees the student, who is thinking about how her parents will hate her once they find out that she dropped out of school.

Then, Josh learns that Viktor tried to make the baby genetically perfect but accidentally killed it, and Mary shouted at him.

Josh then arrives in Mary's dream world, a mystical land of floating islands.

As Josh leaves, he bumps into a man, his face and body badly burned and bandaged.

The man sits down near Kate, and opens his suitcase to reveal three small phials with the parasites in them.

[3] GameSpot praised the visual atmosphere and variety of weapons, but claimed that the motion controls of the game are unnatural and awkward.

[10] Joystiq praised the potential of the motion controls, but stated that the story of the game "is hackneyed at best and nonsensical at worst.