The game serves as a sequel to The Mark of Kri, developed by San Diego Studio where employees at BottleRocket had previously worked.

The narrative focuses on a series of events that take place ten years prior to the events of The Mark of Kri and ten years afterwards with levels taking place in the past feature the older generation of the Rakus, Baumusu, Rau's trainer from The Mark of Kri, and a new character named Griz, Baumusu's mentor.

The story was told by the raven, Kuzo and assisting the Oracle, who was distressed that Rau Utu was slain by unforeseen circumstances.

During the events of The Mark of Kri, further revelations came when Griz rushed for three days back to the Inn where Baumusu, Rongo, the Innkeeper, and Tati (when she was 10 years old) were, to warn Baumusu on the imminent attack on their home, but had arrived too late as Griz was captured by the Kasai during the ambush, presumably rotted inside dungeon of the palace of Yolo Maibisi and Rau's journey into Meifiti to rescue the boy, as he was lured away by the Ganguun Priest himself, before returning to the devastated Inn along with a dying Baumusu, and chasing after and defeating the Necromancer to save Tati at Ratuthusai.

The Oracle revealed as part of Rau's destiny that he was one of the last of the Rakus, and warned Tati to beware of the temptation that came with her curse, that the mark was evil and would seek to manipulate her.

After countless battles against the Kasai, as well as the Ganguun Priests in Daiharu and Rututeihuru, they would finally confront Maibisi at the Heart of Evil itself, Haasa.

In the aftermath, Kuzo narrates "I still have more to tell, but am weary so must leave that for another day" for Tati's destiny either for Good or Evil as the game closes.

Gameplay consists of thirteen levels, in which the player, accompanied by a computer-controlled ally, must battle numerous enemies to progress through the story.

Much like its predecessor, the combat system of Rise of the Kasai revolves around the use of Focus Beams, a gameplay mechanic used to lock on to single or multiple enemies from any direction.

A stealth kill can be performed by sheathing the character's weapon and using the focus beam to assign a flashing attack icon onto an unsuspecting enemy.

[2] To help remain undetected, the player can send out a spirit guide to a certain key-point to scope the environment ahead and monitor enemy positions, armaments, and patrol patterns.

Rise of the Kasai's musical score was composed by Jack Wall,[2][3] Rod Abernethy, Jason Graves,[4] and Mike Reagan[5] with instruments provided by Michael Masley and Mr. Lee Vang.