The station is located adjacent to the Moshe Dayan Interchange on the Ayalon Highway.

Moshe Dayan also serves as a stop on new inter-city services to those cities.

From Ashkelon a new railway line has been built to Beersheva and the station serves trains headed there as well.

A few hundred meters south of the station, a currently unused railway tunnel will allow trains to pass under the Ayalon Highway and travel eastward to Rishon LeZion HaRishonim railway station, from which the new line will continue to reach Modi'in and Jerusalem beyond.

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