Rita Grande (born 23 March 1975) is a former tennis player from Italy.

During her career, Grande won three singles titles and five doubles titles on the WTA Tour.

On 5 November 2001, she reached her best singles ranking of world No.

She played the round of 16 in singles at least once in each of the Grand Slam championships, including twice consecutively at the Australian Open, in 2001 and 2002.

Following a bad elbow injury that kept her away from competition for about ten months, Rita Grande retired from professional sport in October 2005.