The River Anner rises south of Mullinahone and flows westwards to the north of Knockahunna.

It passes under Melbourne Bridge and turns southwards, meeting the Clashawley River in Grangebeg.

The Anner passes under the Limerick–Rosslare railway line and then the N24 near Twomilebridge, draining into the Suir at Killaloan Lower.

[3] The River Anner is a noted salmon and trout fishery.

[4][5][6] The river is memorialised in a Charles Kickham poem, "She lived beside the Anner at the foot of Slievenamon".