River of Death is a 1989 American action film written and directed by Steve Carver and starring Michael Dudikoff.

[1][2] In the nightmarish last days of the Third Reich, a psychotic Nazi scientist (Robert Vaughn) escapes to the impenetrable jungles of the Amazon.

Years later, a mysterious incurable disease breaks out among the natives and adventurer John Hamilton (Michael Dudikoff) is hired to lead investigators on a search for the cause.

Braving bloodthirsty river pirates, hostile native tribes and headhunting cannibals, Hamilton, guides a group of explorers up the deadly Rio del Morte to the fabulous lost Inca city.

"[3] The Los Angeles Times said "this hapless movie's strategy seems to be to squeeze Alistair MacLean's story lugubriously through the send-up style of "Raiders of the Lost Ark" and hope the jungle scenery and desultory hamminess of Pleasence and Herbert Lom (as another villain) will distract the audience from everything else.