[citation needed] In the series, Captain Grey Holden and his crew navigate the vessel called the Enterprise principally along the Mississippi, Missouri, and Ohio Rivers.

Holden and his men encounter interesting characters along the way, including U.S. President Zachary Taylor, General Winfield Scott and a prepresidential Abraham Lincoln.

Unlike most Westerns, which are set after the American Civil War, the story's time frame precedes the conflict, and includes the 1830s and the 1840s.

The series ended on the NBC midseason schedule in January 1961, replaced by a drama about the sectional conflict, The Americans.

Ricardo Montalbán portrayed United States Army Lt. Andre B. Devereaux in "A Night at Trapper's Landing" (November 8, 1959).

The episode features Judson Pratt, as Sergeant Ned Bolger, Stacy Harris as Colonel Nicholson, and Raymond Bailey as General Jacoby, with other roles for character actors Morris Ankrum, R.G.

[6] The Los Angeles Times said it was "produced with the slick vacuity of a B movie with pleasantly inconsequential stories and an utter disregard for the color and background that the Riverboat called for.