"I wanted to write a song that presented a resigned, even joyful look at doom," recalls David Byrne in the liner notes of Once in a Lifetime: The Best of Talking Heads.
Cash Box said that "this marching single which features David Byrne's soothing lead vocal is a curious and circus-ride look at life.
Tina Weymouth and Chris Frantz portray a couple growing older, and masked businessmen pummel each other with briefcases and a runaway shopping cart, as if in their own "road to nowhere".
Some parts were shot in the back yard and pool of actor Stephen Tobolowsky, who was co-writing Byrne's film True Stories at the time.
Director Johnson re-used some of the effects techniques in award-winning videos for Peter Gabriel the following year: "Sledgehammer" and "Big Time".