He is the founder and Lead vocalist of the drum and bass/electronic rock band Pendulum, as well as DJ and co-founder of electro house duo Knife Party formed of Swire and Gareth McGrillen.

Originally from Perth, Western Australia, Swire relocated to the United Kingdom in 2003 with fellow Pendulum co-founders Gareth McGrillen and Paul "El Hornet" Harding.

Swire has since fulfilled a broad spectrum of roles as a member of Pendulum, ranging from songwriting to singing while performing live with an unusual guitar-like MIDI controller – Starr Labs' Ztar Z6S-XPA.

[3] Over the next three years he worked as a record producer for several local drum and bass, breakbeat and metal bands, during which time he occasionally used the stage name "Anscenic".

[5] In 2002, Swire formed drum and bass act Pendulum with fellow Xygen bandmate McGrillen and local DJ Paul "El Hornet" Harding.

After the band's first tour they started work on a second album, In Silico, for which Swire featured as the main vocalist, after already appearing on tracks such as "Spiral", "Hold Your Colour", "Streamline", and "Still Grey" in order to keep a consistent sound.

Swire was also extensively involved in creating publicity material for the new album, as he explained during an interview with Lucy Chakaodza of The Independent.

This can be equated to Rob Swire feeling limited to a genre under the band Pendulum, and he has stated publicly over tweets that he hates the restriction that a fan base can bring, he does enjoy continuing to produce music.

On 9 January 2017, Pendulum confirmed to be reuniting for a world tour and possibly releasing a new album, with Swire also returning.

[11] On 29 June 2018, Pendulum's album, aptly titled "The Reworks" was released, composed solely of remixes from artists such as Skrillex, Moby, Pegboard Nerds, Noisia and the Knife Party alias.

On 17 September 2020, Pendulum released two singles "Driver" and "Nothing for Free", making this the first new material in ten years since Immersion.

A music video for "Nothing for Free" was produced, and the two songs were included in a live set performed by Pendulum at Spitbank Fort on 2 October 2020.

The group's popularity grew considerably when they released the top 5 hit U.K. single, Antidote, in collaboration with Swedish House Mafia.

The duo's third EP, Haunted House, was released on 6 May 2013, and features four tracks: "Power Glove", "LRAD", "EDM Death Machine", and their own VIP mix of "Internet Friends", originally from 100% No Modern Talking.

The song has over 60 million views on YouTube, and reached number 1 on the U.S. dance music charts, and certified 3× Platinum in Canada.