Robert Henry Goldsborough (January 4, 1779 – October 5, 1836) was an American politician from Talbot County, Maryland.

Robert Henry Goldsborough was born on January 4, 1779, at "Myrtle Grove" near Easton, Maryland.

He was educated by private tutors and graduated from St. John's College in Annapolis, Maryland, in 1795.

[1] Goldsborough engaged in agricultural pursuits, and also served as a member of the Maryland House of Delegates in 1804.

He was again elected to the U.S. Senate as an Anti-Jacksonian National Republican (later Whig) to fill the vacancy caused by the resignation of Ezekiel F. Chambers, and served from January 13, 1835, until his death.