With his wife and collaborator Dorothy L. Cheney, he spent years studying the social behavior, communication, and cognition of wild primates in their natural habitat, including more than a decade of field work with baboons in the Okavango Delta of Botswana.
Fascinated by wild primates, Seyfarth then applied to work at Cambridge University with Robert Hinde, who had been the thesis advisor of Jane Goodall.
Having been accepted by Hinde, Seyfarth then spent two years (1972–1974) in the field studying baboons in Mountain Zebra National Park in South Africa, together with Dorothy Cheney, whom he had recently married.
[3] Seyfarth's research and publications were largely based on longterm field studies of primates in the natural habitat, usually in partnership with Cheney.
"[4] From 1992 to 2008, Seyfarth and Cheney studied vocal communication and social structure of chacma baboons, at the Moremi Game Reserve in Botswana.