He currently serves as the Ranking Republican on the Government Administration & Elections,[4] Housing,[5] and the Labor & Public Employees[6] Committees.

Sampson supported the Supreme Court's decisions in Harris v. Quinn, which limited the power of labor unions to collect agency fees.

[3] In 2013, after the Sandy Hook Elementary School massacre, he voted against a bipartisan gun control bill; in 2015, he introduced a failed measure to repeal the law.

[3] In 2019, Sampson and fellow John Kissel were the only senators to vote against "Ethan's Law," a safe storage law requiring gun owners to safely store firearms (whether loaded or unloaded) while not in use; the bill passed 31–2.

[10][11] Sampson has received awards from the Connecticut Citizens Defense League[12] and NRA Institute for Legislative Action.

[13] In 2013, Sampson was one of two state lawmakers who voted against a measure requiring officials to consider the necessity of mitigation for when making water treatment facility funding decisions.

[16] In 2019, Sampson was one of two state Senators who voted against a bill banning the practice of pet leasing in Connecticut.

152 'An Act Concerning the Protection of Warehouse Workers', which, among other provisions, was intended to prohibit "employers from requiring employees to meet quotas that interfere with meal periods, bathroom breaks, or compliance with safety regulations.