[4] His research focuses on Artificial Intelligence, specifically on enabling computers to understand and represent meaning across hundreds of languages, making significant contributions to various fields within Natural Language Processing, including Word Sense Disambiguation, Entity Linking, Semantic Role Labeling and semantic parsing.

At the core of his research lies the goal of making semantic representations of words and sentences independent of the language in which they are written.

More recently, he has focused on Large Language Models (LLMs), leading the Minerva project,[5][6] the first Italian effort for pretraining a LLM from scratch.

[2] Navigli's doctoral thesis focused on devising and evaluating an innovative knowledge-based algorithm for Word Sense Disambiguation, named Structural Semantic Interconnections.

[16] In 2016, Navigli founded Babelscape,[17] a successful university spinoff company, focused on multilingual neuro-symbolic Natural Language Understanding.