[1] Abreu received a law degree from the Universidad Tecnológica de México and worked in the National Retirement Savings System Commission and the PGR.

In 2003, she went into the private sector, working for three years at Megaproyectos del Sureste, S.A. de C.V.; she concurrently served as a councilor on the Campeche Human Rights Commission.

[2] In 2012, voters in Ciudad del Carmen and Campeche's second federal electoral district elected Abreu to the LXII Legislature; though this was initially under the PVEM banner, she switched back to the PRI in September 2012.

[1] In 2018, Rocío Abreu ran as the female Senate candidate for the Todos por México political coalition.

While the coalition had originally opted to give her second priority behind male candidate Christián Castro Bello, a court ruling from the TEPJF required the party to introduce gender parity across the country in terms of how many men and women led its Senate tickets, prompting the ticket to be reversed with Abreu on top.