Roche-lez-Beaupré (French pronunciation: [ʁɔʃ lɛ bopʁe]) is a commune in the Doubs department in the Bourgogne-Franche-Comté region in eastern France.

The commune lies 9 km (5.6 mi) northeast of Besançon on the banks of the Doubs.

The commune is served by the railroad, national highway 83, and the navigable Doubs River.

Industries including fertilizer and metalworking have been established in the commune.

This Doubs geographical article is a stub.