[1][2][3] The art center is also known for its popular Makers & Mentors Exhibitions, which combines notable educators with their current and former students.

In 2007, it initiated First Friday, a monthly citywide gallery night involving up to thirty other art venues throughout the city of Rochester.

In December 2012, the center announced the purchase of its 137 East Ave. facility and the launch of their first-ever capital campaign, The Future Fund.

Each year, 6x6 returns with thousands of original artworks, made and donated by celebrities, international and local artists, designers, college students, youths, and others.

[6] Previous submissions include artworks from George Condo, Andrea Barrett, Wendell Castle, Garth Fagan, Philip Glass, Albert Paley, Joel Seligman, Louise Slaughter, Lovely A. Warren, and Danny Wegman.