Cruz started as a host, together with his younger brother Rayver, in the children's magazine show 5 And Up.

The group, previously named Anime—in reference to the Tagalog word "anim" or "six"—originally consisted six members namely: Rayver Cruz, John Wayne Sace, Emman Abeleda, Sergio Garcia, Mico Aytona, and Mhyco Aquino.

[citation needed] After a year, Cruz along with 14 other celebrity contestants joined the second season of U Can Dance Version 2,[2] where he met and started dating fellow Star Magic talent Dianne Medina.

[4] He made a guest appearance in the "Mambabarang" episode of Komiks Presents: Pedro Penduko at ang mga Engkantao in the same year.

[citation needed] In October 2017, Cruz announced his engagement to actress Dianne Medina after dating since July 23, 2007.