Rodolfo Espinosa Ramírez (1876–1944[1]) was a Nicaraguan politician and former Vice President.

Espinosa ran as the vice presidential candidate of Leonardo Argüello Barreto in the December 1936 elections.

He was elected Mayor of Managua in 1904, and the following year member of the National Congress of Nicaragua for his party: the Liberals.

In the administration of Juan Bautista Sacasa worked against Somoza.

[1] He was the grand master of Nicaraguan freemason lodge from 1902 to 1907.