The Rodovia dos Imigrantes (official designation SP-160) is a highway in the state of São Paulo, Brazil.

The highway has recently been expanded, in one of the most audacious feats of Brazilian highway engineering, with extremely long tunnels and high strutting six-lane bridges constructed over the tropical rain forest, which covers the steep faces of the Serra do Mar, the cliff range that separates the São Paulo plateau from the seaside lowlands.

During sunny weekends, more than one million automobiles commonly cross its near 60 km run, separating the city of São Paulo from the sea.

Although longer than the Anchieta, the Imigrantes is nowadays busier due to its building standards, which permit higher speed limits, and its more direct path to the cities of Santos and Guarujá, the northern coast (with Bertioga), as well as the southern coast (with cities Praia Grande, Mongaguá, and Itanhaém).

It is managed by a state concession to the private company, Ecovias, which also maintains the Rodovia Anchieta; it is, therefore, a toll road.