[1][9] The airport underwent renovations which included a new 110,000 sq ft (10,000 m2) terminal building with room for expansion; work completed in 2009 and designed by CSHQA and the Abell Architectural Group Inc.[10] The new terminal has an observation deck on the second floor, a restaurant for screened and unscreened passengers, and second-story loading bridges.

[11] Two fixed-base operators (FBOs) provide general aviation services on the field: Jet Center MFR, and Million Air (which recently completed its new three-story corporate terminal).

In the year ending December 31, 2020, the airport had 41,563 aircraft operations, average 114 per day: 59% general aviation, 22% airline, 16% air taxi, and less than 1% military.

In the late 1980s and early 1990s United Express operated as NPA, West Air and Mesa flying British Aerospace Jetstreams (19 seat turboprops) directly to both Portland and Seattle.

Aha Airlines offered service between Medford and Reno, NV between October 2021 and August 2022 when it declared bankruptcy.