Rohani binti Abdul Karim (Jawi: روحاني بنت عبدالكريم; born 3 January 1955) is a Malaysian politician who served as the Minister of Women, Family and Community Development, Deputy Minister of Domestic Trade, Cooperatives and Consumerism, Deputy Minister of Agriculture and Agro-based Industries in the Barisan Nasional (BN) administration under former Prime Ministers Abdullah Ahmad Badawi and Najib Razak and former Ministers Ismail Sabri Yaakob, Mustapa Mohamed and Noh Omar from March 2008 to the collapse of the BN administration in May 2018 as well as the Member of Parliament (MP) for Batang Lupar from March 2004 to November 2022 and for Santubong from October 1990 to March 2004.

She then resumed her studies until she obtained her Master of Business Administration (MBA) from Ohio University, Athens, USA.

In the 2004 general election, she had switched to the Batang Lupar, Sri Aman, Sarawak, where she was born, and won uncontested.

She once again won the Batang Lupar parliamentary seat against opposition party representatives in the 2008 general election with 70 percent of her vote in favour of her.

On 9 April 2009, Malaysia's sixth Prime Minister, Datuk Seri Najib Razak, who just held the leadership of the country at that time, entrusted her to take over Tan Lian Hoe's duties as Deputy Minister of Domestic Trade, Co-operatives and Consumerism.