[6] Her second book, Uncommon Ground, a nonfiction work based on her reporting as an anchor of the 2008 Indian TV program of the same name.

[9][6] In 2001, Rohini Nilekani founded Arghyam Foundation, a non-profit that works on water and sanitation issues and is funded by her personal endowment.

[14] Nilekani currently supports 80 civil society organizations working on climate change, gender equity, justice, governance and animal welfare.

[17] In December 2013, Rohini and her husband, Nandan Nilekani donated ₹50 crores to the National Council of Applied Economic Research to build a new India center at its New Delhi campus.

[20][21] She supports around 80 civil society organizations, working in climate change, gender equity, independent media, governance and the animal welfare sector.

[23] In November 2022, Rohini Nilekani along with Kiran Mazumdar-Shaw and Kris Gopalakrishnan collectively donated ₹51 crore to Science Gallery Bengaluru (SGB), a not-for-profit public institution for research-based engagement.

[24] In April 2023, Rohini Nilekani, through the Rohini Nilekani Philanthropies Foundation, made a donation of ₹100 crore to the National Institute of Mental Health and Neurosciences (NIMHANS) in Bengaluru to support and accelerate research and treatment in five major areas of mental health.