It takes its name after Rolighed, a Rococo-style country house from 1770 which is now owned by the university.

Associated with Ladegården, a farm established by Christian IV, although possibly considerably older, it was the first of several "royal roads" in the area.

The other part of the street was renamed Godshåbsvej after Store Godthåb, another country house.

A large site on the south side of the street was reserved for the Royal Veterinarian School.

Landøkonomiske Forsøgslaboratorium (Agricultural Economic Research Laboratory) opened next to Københavns Sygehjem 1882-1883.

From 24 July 1884, Falkoneralléens Sporvejsselskab operated a tram service between Frederiksberg Runddel and Halmtorvet (now Rådhuspladsen) by way of Rolighedsvej.

Frederiksberg Iron Foundry and Machine Factory was founded at Falkoner Allé (No.

The Royal Danish Agricultural Society (Det Kongelige Danske Landhusholdningsselskab) relocated to a building at No.

23) is now home to the University of Copenhagen's Department of Geosciences and Natural Resource Management.

He was also president of the Royal Danish Society for Agriculture (Det Kongelige Danske Landhusholdningsselskab).

The Forum (East) and Frederiksberg (Southwest) metro stations are both located approximately 500 metres from the street.

A new metro station on the City Circle Line will open at Aksel Møllers Have, some 300 m to the west of the street, in 2019.