[2] During the next year, Martínez defeated Richard Boyd, Adisone Sengaroun and Joe Johnson by knockout and Israel Coraliz by unanimous decision, before scoring the first draw of his career against Jose Leonardo Cruz.

This fight was followed by eleven months of inactivity, when he returned to action by defeating Wilfredo Vargas by technical knockout in three rounds.

On November 17, 2006, Martínez fought in the super featherweight division for the first time, defeating Baudel Cárdenas by technical decision in the tenth round.

[2] With this victory, he won the vacant WBO Latino super featherweight title, a regional championship sanctioned by the World Boxing Organization.

After defeating Genaro Trazancos by technical knockout in a non-title fight, he participated in a unification match against Daniel Jimenez.

On August 30, 2008, Martínez defended the NABO super featherweight title against Santos Benavides, winning the contest by technical knockout in the sixth round.

He entered this fight ranked third in the WBO and expected to receive a championship opportunity against then-champion Alex Arthur if he won.

[4] In the fourth round, Martínez scored a knockdown, which was quickly followed by a hook that left Cook partially unconscious.

The contest opened with Gonzalo Munguía, who was physically stronger pursuing direct exchanges, while Martínez employed an uncommon strategy of technical sidestepping and counterattacks.

[6] On September 4, 2010, Martinez travelled to the United Kingdom to defend his WBO title against Scottish contender Ricky Burns (28-2, 7 KO).

Martinez suffered his first professional defeat and dethroned of his world title in Glasgow as Burns emerged victorious after a 12-round decision.

[8] On September 15, 2012, at the Thomas & Mack Center, Paradise, Nevada, U.S.A., Martinez defeated Mexican contender Miguel Beltran, Jr. to win the vacant WBO super featherweight title for a second time.

[15] On September 9, the date of the purse bid, a deal was set for the fight to take place on November 9 at the American Bank Center in Corpus Christi, Texas.

Martinez challenged WBO super featherweight champion Orlando Salido on April 11, 2015, at the Jose Miguel Agrelot Coliseum in San Juan, Puerto Rico.

[24][25] It was announced that Martinez would defend his WBO title against accomplished Ukrainian boxer Vasiliy Lomachenko on June 11, 2016, at The Theater at Madison Square Garden.

[26] Lomachenko outboxed and outclassed Martinez for four rounds, landing left hands and right hooks, using his footwork to keep the range he wanted at all times.

Lomachenko knocked out Martinez with a big right hook in the fifth round becoming a two-division world champion in his seventh pro fight.

[27] According to TMZ Sports in early July 2017, it was reported that Gervonta Davis would feature in the co-main event of Floyd Mayweather Jr. vs. Conor McGregor on August 26, 2017, at the T-Mobile Arena in Paradise, Nevada.

[29] On August 10, Ringtv reported that Davis would instead fight unbeaten prospect Francisco Fonseca (19-0-1, 13 KOs), who at the time was ranked number 7 by the IBF.