The Archdiocese of Las Vegas has two suffragan sees in its ecclesiastical province: the Dioceses of Reno and Salt Lake City.

The first Catholic Mass in southern Nevada was celebrated in 1776 in present-day Laughlin by Francisco Hermenegildo Tomas Garces, traveling from Mexico when the entire region was part of the Spanish Empire.

[4] Bishop Lawrence Scanlan, head of the Apostolic Vicariate of Salt Lake City, established the first parish in Pioche in the late 1880s.

Scanlan said that he chose the name Joan of Arc because the blistering sun in Las Vegas reminded him of her suffering when she was burned at the stake.

The second bishop of Las Vegas was Joseph A. Pepe of the Archdiocese of Santa Fe, named by John Paul II in 2001.

[8] On February 28, 2018, Pope Francis accepted Pepe's letter of resignation as bishop of the Diocese of Las Vegas after he reached the mandatory retirement age of 75.

The plaintiffs claimed that Mark Roberts of Saint Peter the Apostle Parish in Henderson had physically and sexually abused them as boys between 1996 and 1999.