The Roman Catholic Archdiocese of Sherbrooke (Latin: Archidioecesis Sherbrookensis) is a Roman Catholic archdiocese that includes part of the civil province of Quebec and includes the suffragan dioceses of Nicolet and Saint-Hyacinthe.

By 1830, Irish and French Canadian Catholics in the area worshipped at a small chapel dedicated to St. Columban.

In 1874, the Diocese of Sherbrooke was created from the Roman Catholic Archdiocese of Quebec.

The following is a list of the bishops and archbishops of Sherbrooke and their terms of service:

This article about a Roman Catholic diocese in Canada is a stub.