The Roman Catholic Diocese of Caacupé (Latin: Dioecesis Caacupensis) is a Latin Rite suffragan diocese in the ecclesiastical province of Archdiocese of Asunción, which covers all and only Paraguay.

Its cathedral episcopal see is a Minor Basilica and National Shrine: Catedral Basílica Nuestra Señora de los Milagros, dedicated to Our Lady of Miracles, in the city of Caacupé, in Cordillera Department.

As per 2014, it pastorally served 262,724 Catholics (93.0% of 282,481 total) on 4,984 km2 in 20 parishes and 2 missions with 29 priests (24 diocesan, 5 religious), 2 deacons, 44 lay religious (7 brothers, 37 sisters), 6 seminarians.

(all Roman Rite)

This article on a Roman Catholic diocese in Paraguay is a stub.