The Roman Catholic Diocese of Keetmanshoop (Latin: Keetmanshoopen(sis)) is a suffragan diocese in the Latin Rite Ecclesiastical province of the Metropolitan of Windhoek in Namibia, yet depends on the missionary Roman Congregation for the Evangelization of Peoples.

Its cathedral episcopal see is St. Stanislaus Cathedral, in the city of Keetmanshoop.

As per 2015, it pastorally served 42,570 Catholics (23.6% of 180,000 total population) on 264,110 km2 in 11 parishes and 32 missions with 16 priests (3 diocesan, 13 religious), 13 deacons, 65 lay religious (17 brothers, 48 sisters) and 2 seminarists.

(all Roman rite, so far members of a missionary congregation)

This article on a Roman Catholic diocese in Africa is a stub.