The Roman Catholic Diocese of Mukachevo (Latin: Dioecesis Munkacsiensis Latinorum) is a diocese of the Latin Church of the Catholic Church in Ukraine.

This is unique among the Ukrainian dioceses, the remainder of which were all split off from Lviv, which has been associated with Polish culture.

Mukachevo Roman Catholics are mostly members of the Hungarian minority in Ukraine.

Elevated to a diocese in 2002, its first bishop was Antal Majnek until 28 January 2022.

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