The Roman Catholic Archdiocese of the Blessed Assumption (Latin: Archidioecesis Sanctissimae Assumptionis) is an ecclesiastical territory or diocese of the Roman Catholic Church in Paraguay.

[1][2] It was created as the Diocese of Paraguay by Pope Paul III on July 1, 1547, and was elevated to the rank of a metropolitan archdiocese by Pope Pius XI on May 1, 1929, with the suffragan sees of Benjamín Aceval, Caacupé, Carapeguá, Ciudad del Este, Concepción, Coronel Oviedo, Encarnación, San Juan Bautista de las Misiones, San Lorenzo, San Pedro, and Villarrica del Espíritu Santo.

The archdiocese's mother church and thus seat of its archbishop is the Cathedral of Our Lady of the Assumption.

As the only metropolitan in Paraguay, it is the principal episcopal see of that country.

Archbishop Flores succeeded to the see on March 6, 2022.