The Roman Catholic Diocese of Saint-Jérôme (Latin: Dioecesis Sancti Hieronymi Terraebonae) is a Latin rite suffragan of the Archdiocese of Montréal.

Its cathedral episcopal see is Cathédrale Saint-Jérôme, dedicated to Saint Jerome (Hieronumus), in Saint-Jérôme, Quebec.

It was erected on 23 June 1951 as Diocese of Saint-Jérôme (Latin: Sancti Hieronymi Terræbonæ), on territories split off from (its Metropolitan) the Archdiocese of Montréal, the Archdiocese of Ottawa and the Diocese of Mont-Laurier.

As per 2014, it pastorally served 446,000 Catholics (97.2% of 459,000 total) on 2,116 km2 in 35 parishes, 67 priests (52 diocesan, 15 religious), 18 deacons, 118 lay religious (21 brothers, 97 sisters), 3 seminarians.

This article about a Roman Catholic diocese in Canada is a stub.