The Roman Catholic Diocese of St. George's in Grenada (Latin: Dioecesis Sancti Georgii) is a diocese of the Catholic Church that encompasses only and the entirety of Grenada.

It is a suffragan of the Metropolitan Archdiocese of Castries (Saint Lucia) and a member of the Antilles Episcopal Conference.

The diocese depends on the Dicastery for Evangelization.

Its episcopal see is the Immaculate Conception Cathedral, in the national capital of St. George's.

As per 2014, it pastorally served 46,485 Catholics (45.4% of 102,295 total) on 340 km² in 20 parishes and 1 mission with 23 priests (7 diocesan, 16 religious), 8 deacons and 53 lay religious (20 brothers, 33 sisters) .