The Roman Catholic Diocese of San Roque de Presidencia Roque Sáenz Peña is located in the town of San Roque in the city of Presidencia Roque Sáenz Peña, usually referred to as simply Sáenz Peña, in the province of Chaco, Argentina.

On 12 August 1963, Pope Paul VI established the Diocese of Presidencia Roque Sáenz Peña from the Diocese of Resistencia.

Its name was changed to the Diocese of San Roque de Presidencia Roque Sáenz Peña on 28 February 1992 by Blessed John Paul II.

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