The Diocese of Tacuarembó (Latin: Dioecesis Tacuarembiana) is a Latin Church ecclesiastical territory or diocese of the Catholic Church in Uruguay.

It is a suffragan diocese in the ecclesiastical province (covering all Uruguay) of the metropolitan Archdiocese of Montevideo.

The diocese was created in 1960, from the Diocese of Florida and is a suffragan of the Archdiocese of Montevideo.

It covers the Departments of Tacuarembó and Rivera.

This article on a Roman Catholic diocese in Uruguay is a stub.