Romance de Amour is set against a beauty centre operated by three good friends (Aileen Tan, Jacelyn Tay and Pan Lingling).
Aileen Tan plays Kang Li, a beautiful and elegant lady who is successful in her career; however her love life is a mess.
Realizing that Weide will not divorce his wife, Kang Li decides to end the affair for good and starts seeing Zheng Xuelun (Qi Yuwu).
Just when the turmoil surrounding the love triangle finally subsides, Kang Li is diagnosed with cancer, already in its terminal stages.
However, where affairs of the heart are concerned, she has her reservations about men and like Kang Li, she is secretly in love with another man (Huang Weide).