Romas Mažeikis (born 28 April 1964) is a retired Lithuanian international footballer who played as a defender for clubs in the Soviet Union, Austria and Germany.
Born in Gargždai, Mažeikis began playing professional football for FK Žalgiris Vilnius in the Soviet First League.
When Žalgiris left the Soviet league in 1990, he joined Georgian side FC Guria Lanchkhuti for the remainder of the season.
Mažeikis returned to the Soviet Top League with FC Lokomotiv Moscow the following season, appearing in 24 matches as the club finished in last place.
In July 1993, Mažeikis moved to Germany where he would finish his career with VfB Lübeck.