A late comer to Australian rules football, De Iulio only switched from soccer at the age of 16.
[1] He played for both Brunswick and Box Hill in the VFA, winning the Fothergill–Round Medal in 1991, before being drafted by North Melbourne.
Before he played a senior game he was traded to Carlton and made his AFL debut in 1992.
In April 2022 De Iulio was convicted of possession of methamphetamine and the proceeds of crime, and was sentenced to a six month diversion program.
[3] He was pleaded guilty to further drug trafficking charges in 2023 and was given a fine and a good behaviour bond.