Santos wrote songs and produced albums for various artists, including: Daniel Padilla, Regine Velasquez, Vina Morales, Vice Ganda, Ylona Garcia, Kaye Cal, Toni Gonzaga, Martin Nievera, Juris Fernandez, Erik Santos, Jed Madela, Angeline Quinto, and Jaya.
He graduated college in Bicol University with a bachelor's degree in BS Food Technology, he became a manager at a nutrition lab soon after.
Rox's compositions “Hanggang Kailan” performed by Michael Pangilinan (which he co-wrote with fellow songwriter Cynthia Roque) and Vice Ganda's “Boom Panes,” “Karakaraka,” “Push Mo Yan Teh” and “Wag Kang Pabebe” were all massive hits.
He wrote and produced "Akin Ka Na Lang" for local television drama "My Illegal Wife," "Karakaraka" for the film "Bromance" starring Zanjoe Marudo[7] and the theme for "The Amazing Praybeyt Benjamin."
Artists in said label includes Loisa Andalio, Maymay Entrata, Edward Barber, Patrick Quiroz, Ylona Garcia, Kyle Echarri, Maris Racal,[8] McCoy de Leon, Elisse Joson, Kisses Delavin, Rayt Carreon, Chard Ocampo, Andrea Brillantes, Vivoree Esclito, and the music and dance group The Hashtags.