[4] She also served on the UNESCO Commission[8][5] and sat on executive boards ranging from the National Endowment for the Arts to the Los Angeles County Arts Commission[2] to the American Friends of the Hebrew University Board; she also acted as chairperson for a variety of entities, including the Community Relations Committee of the Los Angeles Jewish Community Council[7] and the National Congressional Committee Dinner.

[11] Her Chicago-born mother became a pharmacist as well, despite never pursuing higher education, so she could co-run the drugstore the family had at 9th Street and Western Avenue (in today's Koreatown),[12][13][11] which included a 22-seat lunch counter.

[7][5][3] After college, she gained employment as a recreation director and made plans to go to law school but before that could happen, she deferred enrollment to campaign for Adlai Stevenson,[3] and was subsequently elected[16] to the City Council in 1953.

[22] In 1953, Rosalind Wiener campaigned in the 5th District to succeed Councilman George P. Cronk, with the aid of a swarm of University of Southern California students, and she "pulled a surprise" to finish first in the primary election, ahead of public accountant Elmer Marshrey.

[23] In the final, she won just 52% of the vote and took her seat for a four-year term as the youngest council member ever elected and only the second woman—the first having been Estelle Lawton Lindsey in 1915.

One writer opined that it was Wyman's stand on the council to turn over Chavez Ravine to the Dodgers, and the resulting expulsion of displaced residents, most of them Mexican-Americans, that was "a major—if not decisive— reason" for her loss.

"[24] She had become a vocal critic of Yorty, to the extent that a columnist wrote, 'their vendetta has replaced the La Brea Tar Pits as one of our major tourist attractions.'

"[19] In 1975, after she was widowed, she campaigned to win back her old seat, "but the race turned ugly when Wyman was attacked [...] as an out-of-touch imperialist, more impressed with her national endorsements than with local issues."

[19] Wyman remained attached to the Dodgers and purchased eight season tickets directly through owner Walter O'Malley, paid for by her husband's law firm.

[7] In 1988 and 1989, Wyman served as chair of the benefit Singers Salute the Songwriters, with funds going to the Betty Clooney Foundation for Brain Injuries.