[1] In 1992, George earned a First-Class Honours BA in Modern Languages from Somerville College, Oxford, followed by an MA in international politics in 1994 at the University of Pennsylvania, as a Thouron Scholar and Fulbright Fellow.

Subsequently, she assumed the roles of senior editor and writer at COLORS magazine, a bilingual publication published by the Benetton clothing company.

She has contributed her writing to publications including the Independent on Sunday, Arena, Financial Times, Daily Telegraph, Details, Bad Idea,[4] and UnHerd.

[5] She also served as a war correspondent in Kosovo for Condé Nast Traveler magazine and notably attended Saddam Hussein's birthday party[3] on two occasions.

[6] Until 2010, she held the position of senior editor at large for Tank, a London-based quarterly magazine covering fashion, art, reportage, and culture.

George ended a Substack post criticizing UK politicians Matt Hancock and Suella Braverman by writing:And I wonder whether the current gender fluid trans nonsense and its accompanying violence and lack of debate is because being trans is something to cling to, and when you hold tight to something, you get violent in its defence.

I was told recently that HRT is being exchanged on a kind of black market by men experimenting with taking hormones.

[17] She has characterized the accusation of transphobia as one that's "constantly lobbed at anyone who thinks biology is binary or that women and girls are entitled to single sex changing rooms/sports categories/prisons/refuges etc.

In 2022, she signed a letter to the Society of Authors calling for the removal of its Board of Management Chair over a perceived "sideswipe at JK Rowling".

George wrote of her father:I have a box of his sermons that I keep meaning to read, and I’ve been thinking about him this week not just because of the anniversary of his death, or the fact that he so objected to the Americanization of Mothering Sunday into Mother’s Day that he wrote a sermon about it, but because I have been thinking about codes, and morality, and having an anchor in your life.

[33] Some online readers took issue with the line, "My long Covid is suspected by my GP, since I never actually tested positive ..." George defended herself on Twitter by engaging with critics directly.