The two-story brick house is built in the Italianate style, with a square main block topped by a cupola.

A two-story rear section extends back from the main block, forming a "T".

[2] Rose Hill was built in 1852 for Emory Low, a Louisville dry goods merchant born in Leominster, Massachusetts in 1808.

While Rose Hill was still under construction, Low was killed when an outhouse wall collapsed on him.

[2] Rose Hill was owned by the Seelbach family in the 1940s, but fell into disrepair from the late 1950s until 1975, when it became home to a graphic design firm.