Rose Polenzani (born March 7, 1975, in Waukesha, Wisconsin) is an American folk musician.
She was raised in the Chicago area and attended Knox College before leaving to pursue a singing career.
She has opened for the Indigo Girls, David Gray, Vic Chesnutt, Patty Griffin, Joan Baez, Jonatha Brooke, Kristin Hersh and Shawn Colvin.
Polenzani performed as part of Voices on the Verge, a collaborative musical project with Beth Amsel, Jess Klein, and Erin McKeown.
In 2004, Polenzani toured with Sharon Lewis of the British band Pooka, whom she cites as a major musical influence.