She started her career as a part of ABS-CBN's defunct youth-oriented show Ang TV (1992–1997) together with Jolina Magdangal, Claudine Barretto, Antoinette Taus, etc.
To date, Dahil Mahal Na Mahal Kita was also covered four times by different artists: Rachelle Ann Go for The Gulong Ng Palad (2006) Soundtrack and Zsa Zsa Padilla's rendition for the Afternoon Soap theme Magkano Ang Iyong Dangal?
in 2010, in 2013 by Vice Ganda for the soundtrack of the Primetime series Huwag Ka Lang Mawawala, and in 2018, Jonalyn Viray (aka Jona), for the teleserye Asintado.
In 2000, she revived the Barry Manilow song "Somewhere Down The Road" for the Blockbuster Film "Minsan Minahal Kita" which also was included in the Original Motion Picture Soundtrack; and in 2002, her comeback platinum hit with Star Records "Huwag Ka Nang Magbabalik for the film Ngayong Nandito Ka and Jologs.
In 2010, Bakit Nga Ba Mahal Kita was also re-recorded by Laarni Lozada for the Afternoon Drama "Alyna"; and Kakai Bautista, Philippines' Dental Diva, as her carrier single for her debut album under Star Music in 2017.
Roselle's voice can be classified as soprano as her style is very similar with Regine Velasquez's singing prowess.
On February 13, 2016, she also had a successful concert with other OPM icons entitled LOVE THROWBACK held in PICC (Philippine International Convention Center).