z Rožmberka) was a prominent Bohemian noble family that played an important role in Czech medieval history from the 13th century until 1611.

Members of this family held posts at the Prague royal (and later imperial) court, and were viewed as very powerful lords of the Kingdom of Bohemia.

This branch of the Vítkovci clan was initially founded by Vítek III, the son of Witiko of Prčice.

The coat of arms and emblem of this family was represented by a red five-petalled rose on a silver field, which is still often seen in a considerable part of southern Bohemia.

The decline of the House of Rosenberg began with William and Peter Vok, the sons of Jošt III, both being raised under the guardianship of their uncle, Peter V. William of Rosenberg is generally considered the most significant representative of the family, making the Český Krumlov area the centre of southern Bohemian cultural and political life.