During Fisher's first season on the European Tour he won a Jaguar for a nearest to the pin contest in the 2006 Quinn Direct British Masters.

Fisher started the 2008 season with a joint-second place in the HSBC Champions tournament in Shanghai, beaten by Phil Mickelson in a three-way play-off that also featured Lee Westwood.

In July 2008, Fisher won the European Open on the Heritage Course at The London Golf Club; the first staging of the event at the venue in Kent, England.

Fisher's progress continued in 2009 when he reached the semi-final of the WGC-Accenture Match Play Championship in Arizona, losing to fellow Englishman Paul Casey 4 & 3.

Fisher also finished second at the BMW PGA Championship at Wentworth Club, after shooting a 64 in his final round, which included 6 birdies in the first 12 holes.

[6] At the end of 2009, Fisher won the first Volvo World Match Play Championship that was held away from Wentworth, defeating American Anthony Kim, 4 and 3, in the final at Finca Cortesín Golf Club in Spain.

[8] Fisher qualified for the 2010 European Ryder Cup team, which regained the trophy from the United States at Celtic Manor, Wales, on 4 October.

Fisher lost in a three-man playoff for the BMW Masters, the first of the Final Series events that concluded the European Tour season.

Fisher started the 2015 European Tour season playing in the Nedbank Golf Challenge at the end of 2014, where he finished second behind Danny Willett.