Construction of Rossmoyne Senior High School commenced in 1967 on land that was owned by the Webb family who originally came from Scotland.

[4] Over the years the student catchment areas for Rossmoyne Senior High School were from Lynwood, Willetton, Riverton, Shelley, Bull Creek,[5] Ferndale, southern end of Mount Pleasant, Booragoon and Brentwood.

Students from years seven to ten (inclusive) are required to study a foreign language, with a choice of Chinese, German, French, and Japanese.

The blaze destroyed a double demountable classroom with furniture and computer equipment, the arson squad were investigating the cause.

Coming in from Keith Road, is an oval where students have Physical Education classes and the Performing Arts Centre, opened in 2004.

[citation needed] In 2012, Stage 2 of the Building Plan was completed, which involved a new English and Languages block, a tiered Amphitheatre, a new cafeteria known as "Pereira's Cafe" and an extension of the Performing Arts Centre.

[11][12] On the other side of the school an international-sized soccer field was laid out on the land that was formerly occupied by the ageing demountable buildings.

[13] As of 2013, construction of Stage 3 is underway, which involved building a block for Year 7s[9] in preparation of their move from primary to high school in 2015.