[1] A Grade I listed building, dating in part from the 17th century, it is now an events venue, while the surrounding estate is home to the Rothamsted Research Centre.

The Wittewronges were Calvinists who had fled religious persecution in Ghent in 1564, and had founded a brewery in London.

In the 17th century, Sir John Wittewronge, Anne's son, gave the house its Dutch style.

[2] In 1938 the Harpenden Urban District Council purchased the portion of the estate now known as Rothamsted Park from the Experimental Station, in order to provide playing fields and to preserve an important open space.

[2][3] The New Zealand architect Frederick Strouts used Rothamsted Manor as his inspiration for the design of Ivey Hall, which was built between 1878 and 1880 and is now the main building of Lincoln University.