The Rothermere American Institute is a department of the University of Oxford dedicated to the interdisciplinary and comparative study of the United States of America and its place in the world.

[1] Named after the Harmsworth family, Viscounts Rothermere,[2] it was opened in May 2001 by former US President Bill Clinton.

It hosts conferences, lectures and seminars in the fields of American history, politics, foreign relations, and literature.

Guests and speakers have included Queen Elizabeth, former US President Jimmy Carter, Jesse Jackson, Justice Sandra Day O'Connor and Lord Patten of Barnes.

Oxford University's annual Esmond Harmsworth Lecture in American Arts and Letters is held there.