Signed as heading eastbound, the route initially travels in a southwesterly direction, carrying the name Albion Road.

Route 123 skirts the east side of the airport on a two-lane road, briefly crossing into Smithfield.

This stretch of Route 123 is designated as the Great Road Historic District; while mostly residential, the road passes by an entrance to Lincoln Woods State Park before changing to Front Street and continuing into the Lonsdale section of Lincoln where it intersects with Route 126.

At the far east side of town, the route intersects Route 122 on Lonsdale Avenue, and its name changes to John Street before it bridges the Blackstone River alongside the Blackstone River Greenway and crosses into the town of Cumberland.

The road bridges a railroad alignment within town before intersecting Dexter Street, where the road turns eastward once more and then intersects Route 114's High Street the next block over.