The line runs between the Park and Ride station in White Marsh and Charles Center in Downtown Baltimore.

Local transit buses running between White Marsh and Downtown Baltimore previously operated as the Route 35 line.

The connection between White Marsh and Downtown Baltimore is currently provided by the CityLink Brown and LocalLink 56 lines.

[3][4] Transit service to UMBC is provided by LocalLink 37 and 32, but these lines do not have a direct route to the downtown area.

Route 35 started operating with that designation on May 1, 1970 between Oliver Beach and downtown Baltimore, serving the Philadelphia Road/Pulaski Highway corridor.

[5] In 1970, Bus Route 35 started operating between Franklin Square Hospital Center and downtown along the Philadelphia Road corridor in Baltimore County.

[5] In the city, the line operated along Pulaski Highway and Madison and Monument Streets, serving Johns Hopkins Hospital before reached its terminus at University of Maryland Transit Center.

All trips on this line until the mid-90s were considered to be express service, making limited stops on parts of the route, and requiring payment of an additional fare.

Over the years, certain special branches and deviations were added to selected trips on the line to serve various places, including the Essex Community College campus, Chesaco Park, Marshfield Business Park, Oliver Beach, (this service has been provided by Route 24 since 1988), and King Avenue (in 1994, all trips were extended to King Avenue).

In the fall of 1992, MTA announced that weekend service on Route 35 would be eliminated in January 1993 due to low ridership.

[9] After public outcry resulting from these cuts, MTA arranged for a private contractor to provide weekend service along Philadelphia Road.

In 1997, Route 35 started to make its first comeback from its cuts earlier in the decade when all trips on the line were extended to White Marsh.

At this time, all trips were extended to White Marsh, with short turns no longer being made at the city line.